Avoid Stretch Marks During Pregnancy, Stretch Mark Prevention, Champagne for the Body
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Stretch Marks With Palmitoyl Oligopeptide (Biopeptide-CL)
Stretch Mark Prevention Ingredient: Palmitoyl Oligopeptide-3, Biopeptide-CL
Like Palmitoyl Pentapeptide-3, Biopeptide-CL is a synthetic protein that is a fragment of collagen combined with palmitic acid to make it more lipophillic, to improve its stability and to enhance its affinity towards human skin. As with Palmitoyl Pentapeptide-3, one could look at Biopeptide-CL as a man-made precursor to collagen. Biopeptide-CL was developed through research to identify a substance that would behave similarly to retinoic acid but without its drawbacks, especially in regards to synthesizing collagen. The reported results are as follows: In vitro: Increases collagen production by the fibroblasts by as much as 350%. Increases hyaluronic acid production by the fibroblasts by as much as 146%. In vivo: The following statistics were gathered using image analysis of volunteers who used cremes containing a 3% concentration of Biopeptide-CL for 28 days. Surface roughness --- Reduced 17% Mean depth of wrinkles --- Reduced 23% Depth of main wrinkle --- Reduced 39% Skin thickness --- Increased 4% The increase in skin thickness was considered especially notable and contrasts with the 6% reduction of the skin thickness that occurs after 10 years of aging. The study concludes to state that Biopeptide-CL is a potent active cosmetic ingredient without the adverse effects (including irritation, dehydration or long-term toxicity and instability) characteristic of retinoids.
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