Pregnancy Stretch Mark Prevention, Champagne for the Body
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Pregnancy Stretch Mark Prevention
Acetyl Hexapeptide-3 is used in formulas as a wrinkle preventative as well as a wrinkle reducer as an alternative to injections. It is an optimal ingredient in pregnancy stretch mark prevention. Acetyl Hexapeptide-3 is a mimic of the N-terminal end of SNAP-25, one of three proteins (known as the SNARE complex) that are essential for neurotransmitter release at the synapsis, which is the chemical signal for a muscle to contract. As a wrinkle reducer, studies have shown that Acetyl Hexapeptide-3 at a 10% concentration was able to significantly decrease the depth of wrinkles after 30 days of treatment. The mechanism by which Acetyl Hexapeptide-3 is able to accomplish this is related to the ways in which Acetyl Hexapeptide-3 is able to assist wrinkle prevention. Acetyl Hexapeptide-3 performs this activity in two distinct ways: The first way Acetyl Hexapeptide-3 acts as a wrinkle preventative is by competing with SNAP-25 for a position in the SNARE complex. This destabilizes the SNARE complex, preventing the vesicle from releasing neurotransmitters efficiently, and therefore attenuating muscle contraction. This causes a reduction in facial muscle contraction, which is believed to help prevent the long-term formation of lines and wrinkles. The second way that Acetyl Hexapeptide-3 acts as a wrinkle preventative is by reducing the release of catecholamines (the overproduction of which is known to induce the formation of wrinkles and fine lines in the skin), specifically adrenaline and noradrenaline. Acetyl Hexapeptide-3 is non-toxic and well tolerated by the skin.
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